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One method available to study long-term development is the longitudinalstudy.

The mostcommon variants associated with many different types of human cancers (and miss-ing the p53 interacting domain) are: mdm2-a (lacking exons 4–9), mdm2-b (lackingexons 4–11), and mdm2-c (lacking exons 5–9) (see Table 14.2).

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